SubtiBank SubtiBank
ybdJ [2019-08-27 09:41:45]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

ybdJ [2019-08-27 09:41:45]

two-component response regulator ([SW|OmpR family])
locus
BSU_02000
pI
6.35
mw
26.03 kDa
protein length
223 aa Sequence Blast
gene length
672 bp Sequence Blast
function
unknown
product
two-component response regulator ([SW|OmpR family])
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.1|Two-component system response regulators]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.2|Phosphorylation on an Asp residue]

    • Gene

    Coordinates
    221,258 221,929

    The protein

    Protein family

  • [SW|OmpR family] of two-component response regulators

    • [SW|Domains]

  • Response regulatory domain (aa 5-116) (according to UniProt)

    • Modification

  • phosphorylated by [protein|EA36C28A990EFFAEBFE279467A0B56B6B5F5255D|YbdK] on an Asp residue

    • Effectors of protein activity

  • phosphorylation likely affects DNA-binding activity

    • Structure

  • [PDB|1KGS](from Thermotoga maritima, 32% identity) [pubmed|11839301]

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Biological materials

    Mutant

  • MGNA-B956 (ybdJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1955 NBRP B. subtilis, Japan]
  • BKE02000 ([gene|5F6D14A0B360832F9FD470668B006A628B109A56|ybdJ]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE02000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATTAAAATACGATAACCCT, downstream forward: _UP4_TGAAGCTCAAGACAAAATAT
  • BKK02000 ([gene|5F6D14A0B360832F9FD470668B006A628B109A56|ybdJ]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK02000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATTAAAATACGATAACCCT, downstream forward: _UP4_TGAAGCTCAAGACAAAATAT

    • References

  • 10094672,23504016,11839301